ALLERGIC CONTACT DERMATITIS FROM FORMALDEHYDE EXPOSURE

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Allergic Contact Dermatitis Physiology

Allergic Contact Dermatitis (ACD) involves the penetration of an allergen through the skin surface where it acts as a hapten by binding to epidermal proteins and eliciting, a delayed Type IV hypersensitivity reaction 48 to 120 hours after exposure. This immunologic response involves the activation of Th1 cells with the subsequent release of cytokines resulting in the classic inflammatory reaction.

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Allergic contact dermatitis

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Allergic contact dermatitis.

Allergic contact dermatitis (ACD) is a common occupational and environmental health issue. In common with other forms of allergy the disease progresses in two stages; an initial phase during which sensitization is acquired, followed later (after subsequent exposure to the same chemical allergen) by elicitation of a cutaneous inflammatory reaction. The development of skin sensitization is associ...

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ژورنال

عنوان ژورنال: Journal of IMAB - Annual Proceeding (Scientific Papers)

سال: 2012

ISSN: 1312-773X

DOI: 10.5272/jimab.2012184.255